MAT (medication-assisted treatment)

Dr. Van Doren is experienced in treating addiction and provides medication-assisted treatment (MAT). He is a certified buprenorphine prescriber through SAMHSA and the DEA. A comprehensive approach to treatment and recovery is essential. Dr. Van Doren works with various CD (chemical dependency) and MICD (dual diagnosis) treatment programs as well as licensed chemical dependency counselors. All patients receiving MAT must be actively involved in recovery work, which may include outpatient group therapy, residential treatment, or individual CD counseling.

Commonly Used Medications

Buprenorphine is a mixed partial agonist/antagonist of opioid receptors. It works by binding tightly to receptors and blocking other drugs from having an effect. Because of its mixed agonist/antagonist effects it releives symptoms of withdrawal and cravings.

Naloxone is a non-selective competitive opioid receptor antagonist (blocker) and it is used to block opiate receptors. It can be given in an emergency to reverse the effects of an overdose. It is also added to burprenorphine to prevent abuse. The combination is called Suboxone.

Naltrexone is a competitive opioid receptor antagonist (blocker). It is similar to naloxone. It is used to treated opioid and alcohol use disorders. In addition to blocking the effects of opioid drugs it also reduces the pleasure response (release of dopamine and endorphins) in the nucleus acumbens of the brain. It is used to reduce cravings for drugs like alcohol and opioids. It is also used to treat obesity by reducing the compulsions to overeat. Persons with addictions suffer from dysregulation of the pleasure response pathway in the brain.

Accomprosate is an NMDA receptor agonist and a modulator of GABAa receptors. It is used to treat alcohol abuse and is sold under the name Campral. It it works by reducing anxiety and cravings.

Gabapentin was originally developed to treated epilepsy, but it is more commonly used off lable to treat neuropathic pain, anxiety, and alcohol withdrawal and cravings. It works by reducing the excitability of certain neural pathways via its effects on calcium channels.